43 year old female with Pedal Edema, Generalised Weakness.

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I have been given this case to solve in an attempt to understand the topic of " patient clinical data analysis" to develop my competency in reading and comprehending clinical data including history, clinical findings, investigations and come up with diagnosis and treatment plan.




 43 year old female resident of Narketpally came to OPD with chief complaints of  

Swelling in bilateral lower limbs upto ankle since 15 days 

Generalised weakness since 1 week 


HISTORY OF PRESENTING ILLNESS: 

Patient was apparently asymptomatic 15 days ago. She noticed swelling in her both lower limbs until ankle , insidious in onset , gradually progressive in nature , Pitting type . No aggravating and relieving factors.

H/o generalised weakness since 1 week.

Increased menstrual bleeding since 3 months but duration remained same not associated with clots .

No h/o orthopnea and paroxysmal nocturnal dyspnea.

No h/o decreased urine output, burning micturition .

No H/o nocturia, polyuria 

No H/o nausea, vomiting, loose stools, constipation.

No H/o fever, cough ,cold .

No H/o palpitations, sweating .

No H/O chest pain.

No H/o abdominal distension, abdominal pain.

No H/o hematuria.

No h/o headache,sleep disturbances.


PAST HISTORY: She is a 43 year old lady who was born as an elder daughter in her family completed her education until 10th standard.She has two younger brothers.


At the age of 15 she got married and started living with her husband


In 1995 ,she gave birth to her 1st child (male ) but died after 3 days.(NVD)


In 1997 ,she gave birth to a girl child who died at the age of 6.(NVD)


Later with spacing of 3 years she gave birth to her 3rd child who is currently pursuing degree .(NVD )

In 2002 , she gave birth to her 4th child who is a boy . (NVD)


In 2004, she gave birth to her 5th child who is a boy .  (NVD)


After 9 months of birth of her 5th child, she had suffered from low back pain , itching in vaginal area for which she visited her gynaecologist,got evaluated.Her doctor told her that she has lesion in her uterus and got treated for it .


There were no symptoms related to it until 2019 ,but in 2019 when she noticed intermenstrual bleeding for 2 months she visited her gynaecologist and took medication.

4 years ago , patient had complaints of generalised weakness and visited her local doctor , blood investigations were done and her Hemoglobin was around 6 gm/dl .

So she took iron and folic acid supplements for a month and stopped. 

On June 7 2023 , patient came with similar complaints to our OPD , investigations like complete blood picture,serum electrolytes , creatinine and blood urea were done and was advised to get admitted but she wasn't willing to get admitted.

Not a k/c/o Diabetes Mellitus, Hypertension, Tuberculosis,CAD, Thyroid disorders.

MENSTRUAL HISTORY: 

Menarche - 13 years 

28/5 - regular periods 

Earlier 2- 3  pads / day 

Not associated with clots . 

Since  3  months increased bleeding during periods , duration remained same 

Pads / day  - 4 pads / day ( wholly filled)


PERSONAL HISTORY: 

Diet - mixed  

Breakfast -  4 Idly / 3 dosa with chutney / 2chapathi with curry / upma 

Lunch - 1 cup rice with vegetable curry ( tomato ,potato , okra, bottle guard  ) 

Dinner - 1 cup rice with vegetable curry,curd  rice 

Consumes meat twice or thrice a month .  


Daily intake in  Calories (avg)  

Tea with milk and sugar - 45 cal 

Idli (1) - 135 cal 

Chutney - 331 cal 

Rice -130 cal 

Vegetable curry - 85 cal 

Curd  - 118 cal 

On avg total intake is 1582 cal 

Deficient - 418 cal 

Sleep - Adequate 

Appetite - normal

Bowel and bladder - regular

No addictions

No allergies  


DAILY ROUTINE : 

Earlier patient used to wake up by 6 am ,do her household work ,drunk tea at 7 am eat breakfast by 9 am and go and sit in her general store to look after.later at 1 pm she takes rice with any type of curry ( mostly Vegetables - takes meat once in a week - occasionally) . Again she will go and work in her shop.she works until 9 and leaves the other pending work to her children.she goes home and prepare food . She will have dinner by 10 pm ( some times by 11 pm ) . She will go to bed by 12 in the night .

After she noticed pedal edema , she stopped sitting for long time as she thought that was the cause for it. Because of difficulty in breathing and generalised weakness, she stopped going to her general store and taking rest at home. 



FAMILY HISTORY: 

No significant history  


GENERAL EXAMINATION: 

Patient is conscious, coherent and co-operative.

She is moderately built and moderately nourished.

Pallor - Present  



Icterus - Absent

Cyanosis - Absent 

Clubbing - Absent 

No lymphadenopathy

On examination,edema is present below knee level


    

 





Vitals : 

Temperature - 96.8 ° F

Blood Pressure -110/70 mmHg

Pulse Rate -89 bpm

Respiratory Rate - 16 cpm

SYSTEMIC EXAMINATION: 


Per abdomen:- 

On inspection

Shape of abdomen : flat

Umbilicus : inverted 

Movements of abdomen wall with respiration 

No visible peristalsis, pulsations, sinuses, engorged veins, hernial sites 

On palpation 

No local rise of temperature 

Inspectors findings are confirmed 

Soft and non tender

No palpable mass 

Liver is not palpable 

Spleen is not palpable 

On percussion 

Resonance note heard

On auscultation 

Bowel sounds heard  








CVS Examination: 

Inspection

No raised JVP 

Trachea appears to be central 

The chest wall is bilaterally symmetrical

No dilated veins, scars or sinuses are seen

Palpation- 

Trachea Central in position 

Apex beat is felt in the fifth intercostal space, 1 cm medial to the midclavicular line

Auscultation-

S1 and S2 heard, no  murmurs  heard 


Respiratory Examination: 

Shape of chest is elliptical, b/l symmetrical.

Trachea is central. Expansion of chest is symmetrical

 Bilateral Airway Entry - positive

 Normal vesicular breath sounds 


CNS Examination: 

Conscious

Normal speech.

No neurological deficit found.


PROVISIONAL DIAGNOSIS: 

Anemia under evaluation 

Nutritional? Menstrual blood loss? 


INVESTIGATIONS:  

7 June 2023 .

Complete Blood picture:-



Serum electrolytes 


 


Serum creatinine


Blood urea 


Complete Urine Examination


USG report  


Positive findings - borderline splenomegaly 

Right renal calculi 

ECG 

Heart rate -100 bpm ( tachycardia) 

Normal sinus rhythm 

Normal axis



On 13 June 2023 

Hb- 5gm/dl 

TLC - 5800 

MCV - 61.7 

MCHC - 23.1

MCH - 14.3 

Platelet - 3.0  

Serum iron - 31 micro gram / dl 

Blood urea - 22 mg/dl 

Serum creatinine - 0.6 mg/ dl 

Blood grouping - B +ve 

Serum ferritin - 


Liver function tests : 



Chest x-ray




On 14 June 2023 

Fasting Blood sugar -285 mg/dl  

FINAL DIAGNOSIS: 

Severe Anemia Nutritional? Menorrhagia?

Denovo Diabetes mellitus 



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